PTGFRN Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9P2B2 |
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Clone Names | 100324125 |
Gene ID | 5738 |
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Other Names | Prostaglandin F2 receptor negative regulator, CD9 partner 1, CD9P-1, Glu-Trp-Ile EWI motif-containing protein F, EWI-F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD315, PTGFRN, CD9P1, EWIF, FPRP, KIAA1436 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PTGFRN |
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Synonyms | CD9P1, EWIF, FPRP, KIAA1436 |
Function | Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
PTGFRN inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).
References
Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)Andre, M., et al. J Proteomics 73(1):93-102(2009)Andre, M., et al. Proteomics 7(21):3880-3895(2007)Abache, T., et al. J. Cell. Biochem. 102(3):650-664(2007)Sala-Valdes, M., et al. J. Biol. Chem. 281(28):19665-19675(2006)
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