|Other Names||Sodium- and chloride-dependent glycine transporter 2, GlyT-2, GlyT2, Solute carrier family 6 member 5, SLC6A5, GLYT2, NET1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in medulla, and to a lesser extent in spinal cord and cerebellum|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a sodium- and chloride-dependent glycineneurotransmitter transporter. This integral membrane glycoproteinis responsible for the clearance of extracellular glycine duringglycine-mediated neurotransmission. This protein is found inglycinergic axons and maintains a high presynaptic pool ofneurotransmitter at glycinergic synapses. Mutations in this genecause hyperekplexia; a heterogenous neurological disordercharacterized by exaggerated startle responses and neonatal apnea.
Morgado-Valle, C., et al. J. Neurosci. 30(10):3634-3639(2010)Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Koller, G., et al. Addict Biol 14(4):506-508(2009)Deng, X., et al. BMC Psychiatry 8, 58 (2008) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.