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GCLC Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P48506
Clone Names 100427205
Peptide ID 100427205
Additional Information
Gene ID 2729
Other Names Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCLC, GLCL, GLCLC
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GLCL, GLCLC
Research Areas
Citations (0)

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Glutamate-cysteine ligase, also known asgamma-glutamylcysteine synthetase is the first rate-limiting enzymeof glutathione synthesis. The enzyme consists of two subunits, aheavy catalytic subunit and a light regulatory subunit. This locusencodes the catalytic subunit, while the regulatory subunit isderived from a different gene located on chromosome 1p22-p21.Mutations at this locus have been associated with hemolytic anemiadue to deficiency of gamma-glutamylcysteine synthetase andsusceptibility to myocardial infarction.


Man, B.L., et al. J Clin Neurosci 17(10):1244-1247(2010)Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) :Le, T.M., et al. Mol. Genet. Metab. 101(1):55-61(2010)Fullerton, J.M., et al. Bipolar Disord 12(5):550-556(2010)Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :

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$ 80.00
Cat# BP18483c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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