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SLC6A13 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NSD5 |
|---|---|
| Clone Names | 110726223 |
| Gene ID | 6540 |
|---|---|
| Other Names | Sodium- and chloride-dependent GABA transporter 2, GAT-2, Solute carrier family 6 member 13, SLC6A13, GAT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC6A13 |
|---|---|
| Synonyms | GAT2 |
| Function | Mediates sodium- and chloride-dependent transport of gamma- aminobutyric acid (GABA) (PubMed:17502375, PubMed:22932902). Mediates transport of beta-alanine (PubMed:17502375). Can also mediate transport of taurine and hypotaurine (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:P31649}; Multi-pass membrane protein |
| Tissue Location | Expressed in brain, kidney, lung, liver and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC6A13 terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Pallo, A., et al. Biochem. Biophys. Res. Commun. 385(2):210-214(2009)Christiansen, B., et al. J. Biol. Chem. 282(27):19331-19341(2007)Hoglund, P.J., et al. Biochem. Biophys. Res. Commun. 336(1):175-189(2005)
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