|Other Names||Sodium- and chloride-dependent GABA transporter 2, GAT-2, Solute carrier family 6 member 13, SLC6A13, GAT2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in brain, kidney, lung, liver and testis.|
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Provided below are standard protocols that you may find useful for product applications.
SLC6A13 terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Pallo, A., et al. Biochem. Biophys. Res. Commun. 385(2):210-214(2009)Christiansen, B., et al. J. Biol. Chem. 282(27):19331-19341(2007)Hoglund, P.J., et al. Biochem. Biophys. Res. Commun. 336(1):175-189(2005)
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