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BTG4 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NY30 |
|---|---|
| Clone Names | 110811027 |
| Gene ID | 54766 |
|---|---|
| Other Names | Protein BTG4, BTG family member 4, Protein PC3b, BTG4, PC3B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BTG4 |
|---|---|
| Synonyms | PC3B |
| Function | Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E (By similarity). Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development (PubMed:32502391). |
| Tissue Location | Expressed in oocytes after germinal vesicle breakdown (PubMed:32502391). Expressed in testis and in olfactory epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of theBTG/Tob family. This family has structurally related proteins thatappear to have antiproliferative properties. This encoded proteincan induce G1 arrest in the cell cycle.
References
Xu, Y., et al. Int. J. Cancer (2010) In press :Dong, W., et al. Biochem. Biophys. Res. Commun. 387(1):132-138(2009)Toyota, M., et al. Cancer Res. 68(11):4123-4132(2008)Auer, R.L., et al. Genes Chromosomes Cancer 43(1):1-10(2005)Yoshida, Y., et al. Jpn. J. Cancer Res. 92(6):592-596(2001)
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