|Other Names||Leucine-rich repeat-containing protein 4C, Netrin-G1 ligand, NGL-1, LRRC4C, KIAA1580, NGL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May promote neurite outgrowth of developing thalamic neurons.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression|
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Provided below are standard protocols that you may find useful for product applications.
NGL1 is a specific binding partner for netrin G1 (NTNG1;MIM 608818), which is a member of the netrin family of axonguidance molecules (Lin et al., 2003 [PubMed 14595443]).[suppliedby OMIM].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sokolowski, M., et al. Mol. Psychiatry 15(1):10-11(2010)Hsu, Y.H., et al. PLoS Genet. 6 (6), E1000977 (2010) :Lin, J.C., et al. Nat. Neurosci. 6(12):1270-1276(2003)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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