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LRRC4C Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9HCJ2 |
|---|---|
| Clone Names | 110811117 |
| Gene ID | 57689 |
|---|---|
| Other Names | Leucine-rich repeat-containing protein 4C, Netrin-G1 ligand, NGL-1, LRRC4C, KIAA1580, NGL1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LRRC4C |
|---|---|
| Synonyms | KIAA1580, NGL1 |
| Function | May promote neurite outgrowth of developing thalamic neurons. |
| Cellular Location | Postsynaptic cell membrane; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NGL1 is a specific binding partner for netrin G1 (NTNG1;MIM 608818), which is a member of the netrin family of axonguidance molecules (Lin et al., 2003 [PubMed 14595443]).[suppliedby OMIM].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sokolowski, M., et al. Mol. Psychiatry 15(1):10-11(2010)Hsu, Y.H., et al. PLoS Genet. 6 (6), E1000977 (2010) :Lin, J.C., et al. Nat. Neurosci. 6(12):1270-1276(2003)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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