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PCMTD2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NV79 |
|---|---|
| Clone Names | 110811163 |
| Gene ID | 55251 |
|---|---|
| Other Names | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2, PCMTD2, C20orf36 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PCMTD2 |
|---|---|
| Synonyms | C20orf36 |
| Function | May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S- adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P22061}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PCMTD2 belongs to the L-isoaspartyl/D-aspartyl protein methyltransferase family. There are 3 named isoforms produced by alternative splicing.
References
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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