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RANBP17 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H2T7 |
|---|---|
| Clone Names | 110811182 |
| Gene ID | 64901 |
|---|---|
| Other Names | Ran-binding protein 17, RANBP17 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RANBP17 |
|---|---|
| Function | May function as a nuclear transport receptor. |
| Cellular Location | Cytoplasm. Nucleus. Nucleus, nuclear pore complex |
| Tissue Location | Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The transport of protein and large RNAs through thenuclear pore complexes (NPC) is an energy-dependent and regulatedprocess. The import of proteins with a nuclear localization signal(NLS) is accomplished by recognition of one or more clusters ofbasic amino acids by the importin-alpha/beta complex; see MIM600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays akey role in NLS-dependent protein import. RAN-binding protein-17 isa member of the importin-beta superfamily of nuclear transportreceptors.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Kutay, U., et al. J. Biol. Chem. 275(51):40163-40168(2000)Koch, P., et al. Biochem. Biophys. Res. Commun. 278(1):241-249(2000)
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