|Other Names||LIM/homeobox protein Lhx8, LIM homeobox protein 8, LHX8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in differentiation of certain neurons and mesenchymal cells.|
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Provided below are standard protocols that you may find useful for product applications.
Members of the LIM homeobox gene family, such as LHX8,encode transcription regulators that share common structuralfeatures. They all contain 2 tandemly repeated cysteine-richdouble-zinc finger motifs, called LIM domains, in addition to ahomeodomain. The homeodomain is a DNA-binding domain, and the LIMdomains are essential for regulating the activity of thesemolecules by interacting with other proteins. Members of the LIMhomeobox gene family are required for the patterning or thespecification and differentiation of different cell types duringembryonic development (Zhao et al., 1999 [PubMed10611327]).
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Qin, Y., et al. Fertil. Steril. 89(4):1012-1014(2008)
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