LHX8 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q68G74 |
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Clone Names | 110808010 |
Gene ID | 431707 |
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Other Names | LIM/homeobox protein Lhx8, LIM homeobox protein 8, LHX8 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LHX8 |
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Function | Transcription factor involved in differentiation of certain neurons and mesenchymal cells. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the LIM homeobox gene family, such as LHX8,encode transcription regulators that share common structuralfeatures. They all contain 2 tandemly repeated cysteine-richdouble-zinc finger motifs, called LIM domains, in addition to ahomeodomain. The homeodomain is a DNA-binding domain, and the LIMdomains are essential for regulating the activity of thesemolecules by interacting with other proteins. Members of the LIMhomeobox gene family are required for the patterning or thespecification and differentiation of different cell types duringembryonic development (Zhao et al., 1999 [PubMed10611327]).
References
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Qin, Y., et al. Fertil. Steril. 89(4):1012-1014(2008)
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