ARMCX3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UH62 |
---|---|
Clone Names | 110819045 |
Gene ID | 51566 |
---|---|
Other Names | Armadillo repeat-containing X-linked protein 3, ARM protein lost in epithelial cancers on chromosome X 3, Protein ALEX3, ARMCX3, ALEX3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARMCX3 |
---|---|
Synonyms | ALEX3 |
Function | Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters. |
Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q8BHS6}. Nucleus {ECO:0000250|UniProtKB:Q8BHS6} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ALEX family of proteinswhich may play a role in tumor suppression. The encoded proteincontains a potential N-terminal transmembrane domain and a singleArmadillo (arm) repeat. Other proteins containing the arm repeatare involved in development, maintenance of tissue integrity, andtumorigenesis. This gene is closely localized with other familymembers on the X chromosome. Three transcript variants encoding thesame protein have been identified for this gene. [provided byRefSeq].
References
Mou, Z., et al. J. Biol. Chem. 284(20):13629-13640(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Ross, M.T., et al. Nature 434(7031):325-337(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.