|Other Names||N-acylethanolamine-hydrolyzing acid amidase, 351-, Acid ceramidase-like protein, N-acylsphingosine amidohydrolase-like, ASAH-like protein, N-acylethanolamine-hydrolyzing acid amidase subunit alpha, N-acylethanolamine-hydrolyzing acid amidase subunit beta, NAAA, ASAHL, PLT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N- palmitoylethanolamine > N-myristoylethanolamine > N- lauroylethanolamine = N-stearoylethanolamine > N- arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine.|
|Tissue Location||Expressed in numerous tissues, with highest levels in liver and kidney, followed by pancreas|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an N-acylethanolamine-hydrolyzing enzymewhich is highly similar to acid ceramidase. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Wang, J., et al. J. Biochem. 144(5):685-690(2008)Muller, T.D., et al. Child Adolesc Psychiatry Ment Health 2 (1), 33 (2008) :Schulze, H., et al. Biol. Chem. 388(12):1333-1343(2007)Zhao, L.Y., et al. Biochim. Biophys. Acta 1771(11):1397-1405(2007)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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