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OSBPL11 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BXB4 |
|---|---|
| Clone Names | 110819080 |
| Gene ID | 114885 |
|---|---|
| Other Names | Oxysterol-binding protein-related protein 11, ORP-11, OSBP-related protein 11, OSBPL11, ORP11, OSBP12 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OSBPL11 |
|---|---|
| Synonyms | ORP11, OSBP12 |
| Function | Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25- hydroxycholesterol (PubMed:17428193). |
| Cellular Location | Late endosome membrane. Golgi apparatus, trans-Golgi network membrane. Note=Localizes at the Golgi- late endosome interface |
| Tissue Location | Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present at low levels in subcutaneous and visceral adipose tissue (at protein level)(PubMed:23028956). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the oxysterol-bindingprotein (OSBP) family, a group of intracellular lipid receptors.Like most members, the encoded protein contains an N-terminalpleckstrin homology domain and a highly conserved C-terminalOSBP-like sterol-binding domain.
References
Zhou, Y., et al. Exp. Cell Res. 316(19):3304-3316(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Bouchard, L., et al. Obesity (Silver Spring) 17(7):1466-1472(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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