|Other Names||Oxysterol-binding protein-related protein 11, ORP-11, OSBP-related protein 11, OSBPL11, ORP11, OSBP12|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25- hydroxycholesterol (PubMed:17428193).|
|Cellular Location||Late endosome membrane. Golgi apparatus, trans-Golgi network membrane. Note=Localizes at the Golgi-late endosome interface|
|Tissue Location||Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956) Present at low levels in subcutaneous and visceral adipose tissue (at protein level)(PubMed:23028956).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the oxysterol-bindingprotein (OSBP) family, a group of intracellular lipid receptors.Like most members, the encoded protein contains an N-terminalpleckstrin homology domain and a highly conserved C-terminalOSBP-like sterol-binding domain.
Zhou, Y., et al. Exp. Cell Res. 316(19):3304-3316(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Bouchard, L., et al. Obesity (Silver Spring) 17(7):1466-1472(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.