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PIN4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y237 |
|---|---|
| Clone Names | 110819084 |
| Gene ID | 5303 |
|---|---|
| Other Names | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Par14, hPar14, Parvulin-17, Par17, hPar17, Peptidyl-prolyl cis-trans isomerase Pin4, PPIase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, hEPVH, Rotamase Pin4, PIN4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PIN4 |
|---|---|
| Function | Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double- stranded DNA. |
| Cellular Location | [Isoform 1]: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1 |
| Tissue Location | Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much more abundant than isoform 2 in each tissue analyzed |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the parvulin subfamily ofthe peptidyl-prolyl cis/trans isomerase protein family. The encodedprotein catalyzes the isomerization of peptidylprolyl bonds, andmay play a role in the cell cycle, chromatin remodeling, and/orribosome biogenesis. The encoded protein may play an additionalrole in the mitochondria.
References
Fujiyama-Nakamura, S., et al. Mol. Cell Proteomics 8(7):1552-1565(2009)Kessler, D., et al. BMC Biol. 5, 37 (2007) :Mueller, J.W., et al. BMC Mol. Biol. 7, 9 (2006) :Reimer, T., et al. J. Mol. Biol. 330(5):955-966(2003)Reimer, T., et al. J. Mol. Biol. 330(5):955-966(2003)
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