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IQGAP2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q13576
Clone Names 110819070
Additional Information
Gene ID 10788
Other Names Ras GTPase-activating-like protein IQGAP2, IQGAP2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IQGAP2
Function Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
Tissue Location Isoform 2 expression is enhanced in testis.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the IQGAP family. Theprotein contains three IQ domains, one calponin homology domain,one Ras-GAP domain and one WW domain. It interacts with componentsof the cytoskeleton, with cell adhesion molecules, and with severalsignaling molecules to regulate cell morphology and motility.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Van Laer, L., et al. Eur. J. Hum. Genet. 18(6):685-693(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Jin, S.H., et al. Int. J. Cancer 122(5):1040-1046(2008)

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$ 277.78
Cat# BP18595b
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