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MAX Antibody (C-term Y123) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P61244
Clone Names 109145
Peptide ID 109145
Additional Information
Gene ID 4149
Other Names Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X, MAX, BHLHD4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAX
Synonyms BHLHD4
Function Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Cellular Location Nucleus. Cell projection, dendrite
Tissue Location High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the basichelix-loop-helix leucine zipper (bHLHZ) family of transcriptionfactors. It is able to form homodimers and heterodimers with otherfamily members, which include Mad, Mxi1 and Myc. Myc is anoncoprotein implicated in cell proliferation, differentiation andapoptosis. The homodimers and heterodimers compete for a common DNAtarget site (the E box) and rearrangement among these dimer formsprovides a complex system of transcriptional regulation. Multiplealternatively spliced transcript variants have been described forthis gene but the full-length nature for some of them is unknown.


Ting, Y., et al. Biochem. Biophys. Res. Commun. 394(3):606-611(2010)Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)Yang, H., et al. Hepatology 49(3):860-870(2009)Polasek, O., et al. Croat. Med. J. 50(1):7-16(2009)Gordan, J.D., et al. Cancer Cell 11(4):335-347(2007)

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$ 80.00
Cat# BP18607b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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