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CNPY3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BT09 |
|---|---|
| Clone Names | 110811045 |
| Gene ID | 10695 |
|---|---|
| Other Names | Protein canopy homolog 3, CTG repeat protein 4a, Expanded repeat-domain protein CAG/CTG 5, Protein associated with TLR4, Trinucleotide repeat-containing gene 5 protein, CNPY3, CTG4A, ERDA5, PRAT4A, TNRC5 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CNPY3 |
|---|---|
| Synonyms | CTG4A, ERDA5, PRAT4A, TNRC5 |
| Function | Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity). |
| Cellular Location | Endoplasmic reticulum. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PRAT4A is associated with the immature form of TLR4 (MIM603030) and regulates its cell surface expression (Wakabayashi etal., 2006 [PubMed 16849487]).
References
Wakabayashi, Y., et al. J. Immunol. 177(3):1772-1779(2006)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)Margolis, R.L., et al. Hum. Genet. 100(1):114-122(1997)
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