Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
SYCP2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BX26 |
|---|---|
| Clone Names | 110811234 |
| Gene ID | 10388 |
|---|---|
| Other Names | Synaptonemal complex protein 2, SCP-2, Synaptonemal complex lateral element protein, hsSCP2, SYCP2, SCP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SYCP2 |
|---|---|
| Synonyms | SCP2 |
| Function | Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9CUU3}. Chromosome {ECO:0000250|UniProtKB:Q9CUU3}. Note=In axial/lateral elements of the tripartite segments of synaptonemal complexes {ECO:0000250|UniProtKB:Q9CUU3} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The synaptonemal complex is a proteinaceous structure thatlinks homologous chromosomes during the prophase of meiosis. Theprotein encoded by this gene is a major component of thesynaptonemal complex and may bind DNA at scaffold attachmentregions. The encoded protein requires synaptonemal complex protein3, but not 1, for inclusion in the synaptonemal complex. [providedby RefSeq].
References
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Deloukas, P., et al. Nature 414(6866):865-871(2001)Schalk, J.A., et al. Mamm. Genome 10(6):642-644(1999)Offenberg, H.H., et al. Nucleic Acids Res. 26(11):2572-2579(1998)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
