|Other Names||Synaptonemal complex protein 2, SCP-2, Synaptonemal complex lateral element protein, hsSCP2, SYCP2, SCP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity).|
|Cellular Location||Nucleus. Chromosome. Note=In axial/lateral elements of the tripartite segments of synaptonemal complexes.|
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Provided below are standard protocols that you may find useful for product applications.
The synaptonemal complex is a proteinaceous structure thatlinks homologous chromosomes during the prophase of meiosis. Theprotein encoded by this gene is a major component of thesynaptonemal complex and may bind DNA at scaffold attachmentregions. The encoded protein requires synaptonemal complex protein3, but not 1, for inclusion in the synaptonemal complex. [providedby RefSeq].
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Deloukas, P., et al. Nature 414(6866):865-871(2001)Schalk, J.A., et al. Mamm. Genome 10(6):642-644(1999)Offenberg, H.H., et al. Nucleic Acids Res. 26(11):2572-2579(1998)
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