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SLC31A2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O15432
Clone Names 110726219
Additional Information
Gene ID 1318
Other Names Probable low affinity copper uptake protein 2, Copper transporter 2, hCTR2, Solute carrier family 31 member 2, SLC31A2, COPT2, CTR2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC31A2 (HGNC:11017)
Function Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer (PubMed:17944601, PubMed:17617060). Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity).
Cellular Location Membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Plasma membrane localization is partial
Tissue Location Ubiquitous with high expression in placenta and heart.
Research Areas
Citations (0)
citation

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Background

SLC31A2 is involved in low-affinity copper uptake (Potential).

References

Blair, B.G., et al. Clin. Cancer Res. 15(13):4312-4321(2009)Bertinato, J., et al. Biochem. J. 409(3):731-740(2008)van den Berghe, P.V., et al. Biochem. J. 407(1):49-59(2007)Zhou, B., et al. Proc. Natl. Acad. Sci. U.S.A. 94(14):7481-7486(1997)

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$ 277.78
Cat# BP18633c
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