|Other Names||Disks large-associated protein 3, DAP-3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95-associated protein 3, SAPAP3, DLGAP3, DAP3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell junction, synapse. Note=Postsynaptic density of neuronal cells.|
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DLGAP3 may play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Bienvenu, O.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (5), 710-720 (2009) :Zuchner, S., et al. Mol. Psychiatry 14(1):6-9(2009)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Bongiorno-Borbone, L., et al. Biochem. Biophys. Res. Commun. 337(2):641-646(2005)
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