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Synthetic peptide
- SPECIFICATION
- CITATIONS
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- BACKGROUND
| Primary Accession | Q15437 |
|---|---|
| Clone Names | 110717177 |
| Peptide ID | 110717177 |
| Gene ID | 10483 |
|---|---|
| Other Names | Protein transport protein Sec23B, SEC23-related protein B, SEC23B |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SEC23B |
|---|---|
| Function | Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity). |
| Cellular Location | Golgi apparatus membrane. Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the SEC23subfamily of the SEC23/SEC24 family, which is involved in vesicletrafficking. The encoded protein has similarity to yeast Sec23pcomponent of COPII. COPII is the coat protein complex responsiblefor vesicle budding from the ER. The function of this gene producthas been implicated in cargo selection and concentration. Multiplealternatively spliced transcript variants have been identified inthis gene.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Fermo, E., et al. Blood Cells Mol. Dis. 45(1):20-22(2010)Bianchi, P., et al. Hum. Mutat. 30(9):1292-1298(2009)Schwarz, K., et al. Nat. Genet. 41(8):936-940(2009)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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