|Other Names||Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2, HMGN2, HMG17|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation|
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Provided below are standard protocols that you may find useful for product applications.
HMGN2 binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation (By similarity).
Rattner, B.P., et al. Mol. Cell 34(5):620-626(2009)Ueda, T., et al. Mol. Cell. Biol. 28(9):2872-2883(2008)Cherukuri, S., et al. Mol. Biol. Cell 19(5):1816-1824(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Porkka, K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(11):7444-7449(2002)
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