|Other Names||Coronin-1C, Coronin-3, hCRNN4, CORO1C, CRN2, CRNN4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in cytokinesis, motility, and signal transduction.|
|Cellular Location||Cell membrane. Cell projection, lamellipodium Cytoplasm, cytoskeleton. Note=All isoforms localize in a diffuse and punctate pattern in the cytosol and are highly enriched in F-actin-rich areas. Isoform 3 colocalizes with the thin filaments of the sarcomere and with the postsynaptic area and the junctional sarcoplasm of motor end plates|
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This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation.
Luan, S.L., et al. J. Pathol. 222(2):166-179(2010)Wu, L., et al. Zhonghua Gan Zang Bing Za Zhi 18(7):516-519(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Samarin, S.N., et al. Biochem. Biophys. Res. Commun. 391(1):394-400(2010)
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