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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   DNAJC10 Antibody (N-term) Blocking Peptide   

DNAJC10 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IXB1
Clone Names 110819059
Peptide ID 110819059
Additional Information
Gene ID 54431
Other Names DnaJ homolog subfamily C member 10, 184-, Endoplasmic reticulum DNA J domain-containing protein 5, ER-resident protein ERdj5, ERdj5, Macrothioredoxin, MTHr, DNAJC10, ERDJ5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DNAJC10
Synonyms ERDJ5
Function Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
Cellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:12411443, ECO:0000269|PubMed:23769672}
Research Areas
Citations (0)

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This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5.


Wang, M., et al. J. Biol. Chem. 284(48):33377-33383(2009)Thomas, C.G., et al. J. Biol. Chem. 284(10):6282-6290(2009)Ushioda, R., et al. Science 321(5888):569-572(2008)Dong, M., et al. Mol. Biol. Cell 19(6):2620-2630(2008)Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 80.00
Cat# BP18675a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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