Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
GTF3A Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q92664 |
|---|---|
| Clone Names | 110819103 |
| Gene ID | 2971 |
|---|---|
| Other Names | Transcription factor IIIA, TFIIIA, GTF3A |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GTF3A |
|---|---|
| Function | Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III- dependent transcription and may also maintain the transcription of other genes (PubMed:24120868). Also binds the transcribed 5S RNA's (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene is a zinc finger protein withnine Cis[2]-His[2] zinc finger domains. It functions as an RNApolymerase III transcription factor to induce transcription of the5S rRNA genes. The protein binds to a 50 bp internal promoter inthe 5S genes called the internal control region (ICR), andnucleates formation of a stable preinitiation complex. This complexrecruits the TFIIIC and TFIIIB transcription factors and RNApolymerase III to form the complete transcription complex. Theprotein is thought to be translated using a non-AUG translationinitiation site in mammals based on sequence analysis, proteinhomology, and the size of the purified protein. [provided byRefSeq].
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)Newton-Cheh, C., et al. BMC Med. Genet. 8 SUPPL 1, S7 (2007) :Weser, S., et al. Nucleic Acids Res. 31(9):2408-2416(2003)Hanas, J.S., et al. Gene 282 (1-2), 43-52 (2002) :Moreland, R.J., et al. Nucleic Acids Res. 28(9):1986-1993(2000)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
