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GMCL1L Antibody (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NEA9 |
|---|---|
| Clone Names | 110826162 |
| Other Names | Putative germ cell-less protein-like 1-like, GMCL1P1, GCL, GMCL1L |
|---|---|
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GMCL2 (HGNC:19717) |
|---|---|
| Synonyms | GCL, GMCL1L, GMCL1P1 |
| Function | Possible function in spermatogenesis. Probable substrate- specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). |
| Cellular Location | Nucleus matrix {ECO:0000250|UniProtKB:Q920G9}. |
| Tissue Location | Expressed predominantly in testis. |
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Provided below are standard protocols that you may find useful for product applications.
References
GMCL1L is possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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