|Other Names||Tumor protein D53, hD53, Tumor protein D52-like 1, TPD52L1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the tumor protein D52(TPD52) family. The encoded protein contains a coiled-coil domainand may form homo- or hetero-dimer with TPD52 family members. Theprotein is reported to be involved in cell proliferation andcalcium signaling. It also interacts with the mitogen-activatedprotein kinase kinase kinase 5 (MAP3K5/ASK1) and positivelyregulates MAP3K5-induced apoptosis. Multiple alternatively splicedtranscript variants have been observed, but the full-length natureof some variants has not yet been determined.
Barbaric, D., et al. Leuk. Res. 30(11):1355-1363(2006)Cao, Q., et al. Biochem. Biophys. Res. Commun. 344(3):798-806(2006)Boutros, R., et al. Exp. Cell Res. 310(1):152-165(2005)Cho, S., et al. J. Biol. Chem. 279(16):16050-16056(2004)Boutros, R., et al. J. Mol. Biol. 332(3):675-687(2003)
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