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AGPAT5 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NUQ2
Clone Names 110826009
Additional Information
Gene ID 55326
Other Names 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, 1-AGP acyltransferase 5, 1-AGPAT 5, Lysophosphatidic acid acyltransferase epsilon, LPAAT-epsilon, AGPAT5
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGPAT5
Function Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor (PubMed:21173190). Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl- CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA (PubMed:21173190). Activity toward lysophosphatidylglycerol not detectable (PubMed:21173190).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope Mitochondrion
Tissue Location Widely expressed.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the1-acylglycerol-3-phosphate O-acyltransferase family. This integralmembrane protein converts lysophosphatidic acid to phosphatidicacid, the second step in de novo phospholipid biosynthesis.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :Agarwal, A.K., et al. Arch. Biochem. Biophys. 449 (1-2), 64-76 (2006) :Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Lu, B., et al. Biochem. J. 385 (PT 2), 469-477 (2005) :Leung, D.W. Front. Biosci. 6, D944-D953 (2001) :

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$ 277.78
Cat# BP18759a
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