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AGPAT5 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NUQ2
Clone Names 110826009
Peptide ID 110826009
Additional Information
Gene ID 55326
Other Names 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, 1-AGP acyltransferase 5, 1-AGPAT 5, Lysophosphatidic acid acyltransferase epsilon, LPAAT-epsilon, AGPAT5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGPAT5
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope. Mitochondrion
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

This gene encodes a member of the1-acylglycerol-3-phosphate O-acyltransferase family. This integralmembrane protein converts lysophosphatidic acid to phosphatidicacid, the second step in de novo phospholipid biosynthesis.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :Agarwal, A.K., et al. Arch. Biochem. Biophys. 449 (1-2), 64-76 (2006) :Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Lu, B., et al. Biochem. J. 385 (PT 2), 469-477 (2005) :Leung, D.W. Front. Biosci. 6, D944-D953 (2001) :

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$ 80.00
Cat# BP18759a
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