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DMWD Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q09019 |
|---|---|
| Clone Names | 110826103 |
| Gene ID | 1762 |
|---|---|
| Other Names | Dystrophia myotonica WD repeat-containing protein, Dystrophia myotonica-containing WD repeat motif protein, Protein 59, Protein DMR-N9, DMWD, DM9 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DMWD (HGNC:2936) |
|---|---|
| Synonyms | DM9 |
| Function | Regulator of the deubiquitinating USP12/DMWD/WDR48 complex (PubMed:33844468). Functions as a cofactor that promotes USP12 enzymatic activity (PubMed:33844468). |
| Cellular Location | Cytoplasm. Nucleus. Perikaryon {ECO:0000250|UniProtKB:Q08274}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q08274}. Note=Localizes mainly to the cytoplasm however shuttles between the cytoplasm and nucleus (PubMed:33844468) In neurons, shows punctate expression throughout the cell body, nucleus and dendrites. Not detected in axons. {ECO:0000250|UniProtKB:Q08274, ECO:0000269|PubMed:33844468} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DMWD could have a regulatory function in meiosis.
References
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)Grimwood, J., et al. Nature 428(6982):529-535(2004)Wansink, D.G., et al. Cytogenet. Genome Res. 100 (1-4), 230-242 (2003) :Eriksson, M., et al. Biochem. Biophys. Res. Commun. 286(5):1177-1182(2001)
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