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IRG1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession A6NK06
Clone Names 110826209
Peptide ID 110826209
Additional Information
Gene ID 730249
Other Names Cis-aconitate decarboxylase, CAD, Aconitate decarboxylase, Cis-aconitic acid decarboxylase, Immune-responsive gene 1 protein, IRG1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRG1
Function Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)- mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; IRG1- mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Cellular Location Mitochondrion.
Tissue Location Expressed in LPS-tolerized macrophages (at protein level). Expressed in peripheral blood mononuclear cells (PBMCs), microglia and macrophage cells
Research Areas
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The function of this protein remains unknown.

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$ 80.00
Cat# BP18784c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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