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CRADD Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P78560
Clone Names 100427317
Peptide ID 100427317
Additional Information
Gene ID 8738
Other Names Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD, RAIDD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RAIDD
Function Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Cellular Location Cytoplasm. Nucleus
Tissue Location Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney
Research Areas
Citations (0)

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The protein encoded by this gene is a death domain(CARD/DD)-containing protein and has been shown to induce cellapoptosis. Through its CARD domain, this protein interacts with,and thus recruits, caspase 2/ICH1 to the cell death signaltransduction complex that includes tumor necrosis factor receptor 1(TNFR1A), RIPK1/RIP kinase, and numbers of other CARDdomain-containing proteins.


Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Jang, T.H., et al. Biochim. Biophys. Acta 1804(7):1557-1563(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Heikaus, S., et al. Cell. Oncol. 32 (1-2), 29-42 (2010) :

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$ 80.00
Cat# BP18802c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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