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STX4 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q12846
Clone Names 100617283
Peptide ID 100617283
Additional Information
Gene ID 6810
Other Names Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STX4
Synonyms STX4A
Function Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Cellular Location Cell membrane; Single-pass type IV membrane protein
Tissue Location Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
Research Areas
Citations (0)

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Background

Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.

References

Evesson, F.J., et al. J. Biol. Chem. 285(37):28529-28539(2010)Kennedy, M.J., et al. Cell 141(3):524-535(2010)Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)Cooper, G.M., et al. Blood 112(4):1022-1027(2008)Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)

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$ 80.00
Cat# BP18817c
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