|Other Names||ADP/ATP translocase 1, ADP, ATP carrier protein 1, ADP, ATP carrier protein, heart/skeletal muscle isoform T1, Adenine nucleotide translocator 1, ANT 1, Solute carrier family 25 member 4, SLC25A4, ANT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the mitochondrial carriersubfamily of solute carrier protein genes. The product of this genefunctions as a gated pore that translocates ADP from themitochondrial matrix into the cytoplasm. The protein forms ahomodimer embedded in the inner mitochondria membrane. Mutations inthis gene have been shown to result in autosomal dominantprogressive external opthalmoplegia and familial hypertrophiccardiomyopathy.
Valenti, D., et al. Biochem. J. 431(2):299-310(2010)Wang, W., et al. Nucleic Acids Res. (2010) In press :Forlani, G., et al. Hum. Mol. Genet. 19(16):3114-3123(2010)Lena, A., et al. FEBS J. 277(13):2853-2867(2010)Kruger, J., et al. Mol Neurodegener 5, 8 (2010) :
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