|Other Names||Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF, RALGDS, KIAA1308, RGF|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide dissociation stimulators (GDSs, orexchange factors), such as RALGDS, are effectors of Ras-relatedGTPases (see MIM 190020) that participate in signaling for avariety of cellular processes.
Fuentes, G., et al. Trends Biochem. Sci. 34(11):533-539(2009)Maehama, T., et al. J. Biol. Chem. 283(50):35053-35059(2008)Rondaij, M.G., et al. Blood 112(1):56-63(2008)Omholt, K., et al. Melanoma Res. 17(6):410-412(2007)Yin, J., et al. Mol. Cell. Biol. 27(21):7538-7550(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.