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RALGDS Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q12967
Clone Names 100617311
Peptide ID 100617311
Additional Information
Gene ID 5900
Other Names Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF, RALGDS, KIAA1308, RGF
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1308, RGF
Function Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q03385}. Nucleus {ECO:0000250|UniProtKB:Q03385}. Note=Localizes mainly in the peripheral region of the cytoplasmic membrane in oocytes and in preimplantation embryos until the 8-cell stage. Between the late 1-cell and the early 2-cell stages, nuclear localization becomes stronger. After the 4-cell stage, not detected in the nucleus. {ECO:0000250|UniProtKB:Q03385}
Research Areas
Citations (0)

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Guanine nucleotide dissociation stimulators (GDSs, orexchange factors), such as RALGDS, are effectors of Ras-relatedGTPases (see MIM 190020) that participate in signaling for avariety of cellular processes.


Fuentes, G., et al. Trends Biochem. Sci. 34(11):533-539(2009)Maehama, T., et al. J. Biol. Chem. 283(50):35053-35059(2008)Rondaij, M.G., et al. Blood 112(1):56-63(2008)Omholt, K., et al. Melanoma Res. 17(6):410-412(2007)Yin, J., et al. Mol. Cell. Biol. 27(21):7538-7550(2007)

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$ 80.00
Cat# BP18831c
Availability: In Stock
Bulk Size
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