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FRS2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8WU20
Clone Names 100617317
Peptide ID 100617317
Additional Information
Gene ID 10818
Other Names Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1, FRS2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FRS2
Function Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Cellular Location Endomembrane system. Note=Cytoplasmic, membrane-bound
Tissue Location Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis
Research Areas
Citations (0)

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Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.


Zhou, W., et al. Cell Res. 19(10):1165-1177(2009)Cha, J.Y., et al. J. Biol. Chem. 284(10):6227-6240(2009)Li, M., et al. J. Dermatol. Sci. 53(3):182-191(2009)Turner, S.T., et al. Hypertension 52(2):359-365(2008)Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)

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$ 80.00
Cat# BP18833c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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