|Other Names||Keratin, type I cuticular Ha1, Hair keratin, type I Ha1, Keratin-31, K31, KRT31, HHA1, HKA1, KRTHA1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HHA1, HKA1, KRTHA1|
|Tissue Location||Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of thekeratin gene family. As a type I hair keratin, it is an acidicprotein which heterodimerizes with type II keratins to form hairand nails. The type I hair keratins are clustered in a region ofchromosome 17q12-q21 and have the same direction of transcription.
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)Lim, J., et al. Cell 125(4):801-814(2006)Cribier, B., et al. J. Invest. Dermatol. 122(5):1078-1083(2004)Langbein, L., et al. J. Biol. Chem. 274(28):19874-19884(1999)
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