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PRICKLE1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96MT3
Clone Names 110901080
Peptide ID 110901080
Additional Information
Gene ID 144165
Other Names Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1, PRICKLE1, RILP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RILP
Function Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
Cellular Location Nucleus membrane. Cytoplasm, cytosol. Note=A smaller amount is detected in the cytosol
Tissue Location Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).
Research Areas
Citations (0)

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This gene encodes a nuclear receptor that may be anegative regulator of the Wnt/beta-catenin signaling pathway. Theencoded protein localizes to the nuclear membrane and has beenimplicated in the nuclear trafficking of the transcriptionrepressors REST/NRSF and REST4. Mutations in this gene have beenlinked to progressive myoclonus epilepsy. Alternate splicingresults in multiple transcript variants. A pseudogene of this geneis found on chromosome 3.


Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010)Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :Perry, J.R., et al. Diabetes 58(6):1463-1467(2009)Narimatsu, M., et al. Cell 137(2):295-307(2009)Shimojo, M. J. Biol. Chem. 283(50):34880-34886(2008)

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$ 80.00
Cat# BP18864b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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