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PTPLAD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9P035
Clone Names 110901088
Peptide ID 110901088
Additional Information
Gene ID 51495
Other Names Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3, 3-hydroxyacyl-CoA dehydratase 3, HACD3, Butyrate-induced protein 1, B-ind1, hB-ind1, Protein tyrosine phosphatase-like protein PTPLAD1, Protein-tyrosine phosphatase-like A domain-containing protein 1, PTPLAD1, BIND1, HACD3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HACD3 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:24175}
Function Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Highly expressed in testis, kidney, brain, liver and weakly in skeletal muscle, spleen and heart. No expression detected in leukocytes.
Research Areas
Citations (0)

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Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression.


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)Taguwa, S., et al. J. Virol. 83(20):10427-10436(2009)Taguwa, S., et al. J. Virol. 82(6):2631-2641(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Sabbah, M., et al. Gene 374, 128-133 (2006) :

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$ 80.00
Cat# BP18866a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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