KIF3A Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y496 |
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Clone Names | 100623244 |
Gene ID | 11127 |
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Other Names | Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A, KIF3A, KIF3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KIF3A |
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Synonyms | KIF3 |
Function | Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium {ECO:0000250|UniProtKB:P28741}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the subdistal appendage region of the centriole. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
References
Ridruechai, C., et al. Genes Immun. 11(5):416-422(2010)Hirokawa, N., et al. Cold Spring Harb Perspect Biol 1 (1), A000802 (2009) :Sathish, N., et al. PLoS Pathog. 5 (3), E1000332 (2009) :Tanuma, N., et al. Oncogene 28(5):752-761(2009)Schonteich, E., et al. J. Cell. Sci. 121 (PT 22), 3824-3833 (2008) :
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