|Other Names||Stromal membrane-associated protein 1, SMAP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity).|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Detected in bone marrow, adrenal gland, trachea, lymph node, spinal cord, peripheral blood leukocytes, thyroid and stomach.|
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The protein encoded by this gene is similar to the mousestromal membrane-associated protein-1. This similarity suggeststhat this human gene product is also a type II membraneglycoprotein involved in the erythropoietic stimulatory activity ofstromal cells. Alternate splicing results in multiple transcriptvariants encoding different isoforms.
Barragan, I., et al. Int. J. Mol. Med. 16(6):1163-1167(2005)Tanabe, K., et al. Mol. Biol. Cell 16(4):1617-1628(2005)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Mungall, A.J., et al. Nature 425(6960):805-811(2003)Marcos, I., et al. Gene 292 (1-2), 167-171 (2002) :
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