|Other Names||Vesicle-associated membrane protein-associated protein B/C, VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C, VAPB|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane.|
|Tissue Location||Ubiquitous. Isoform 1 predominates.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a type IV membraneprotein found in plasma and intracellular vesicle membranes. Theencoded protein is found as a homodimer and as a heterodimer withVAPA. This protein also can interact with VAMP1 and VAMP2 and maybe involved in vesicle trafficking.
Millecamps, S., et al. J. Med. Genet. 47(8):554-560(2010)Langou, K., et al. J. Neurochem. 114(3):795-809(2010)Tsai, C.P., et al. Neurobiol. Aging (2010) In press :Nachreiner, T., et al. Biochem. Biophys. Res. Commun. 394(3):703-708(2010)Funke, A.D., et al. Clin. Genet. 77(3):302-303(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.