S1PR2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95136 |
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Clone Names | 120111183 |
Gene ID | 9294 |
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Other Names | Sphingosine 1-phosphate receptor 2, S1P receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Sphingosine 1-phosphate receptor Edg-5, S1P receptor Edg-5, S1PR2, EDG5 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | S1PR2 |
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Synonyms | EDG5 |
Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617). When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis (PubMed:10617617). Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251). Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the G protein-coupledreceptors, as well as the EDG family of proteins. This proteinparticipates in sphingosine 1-phosphate-induced cell proliferation,survival, and transcriptional activation
References
Oskeritzian, C.A., et al. J. Exp. Med. 207(3):465-474(2010)McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Cattoretti, G., et al. Cancer Res. 69(22):8686-8692(2009)Randriamboavonjy, V., et al. Basic Res. Cardiol. 104(3):333-340(2009)Li, M.H., et al. Mol. Cancer Res. 6(10):1649-1656(2008)
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