|Other Names||FAS-associated factor 2, Protein ETEA, UBX domain-containing protein 3B, UBX domain-containing protein 8, FAF2, ETEA, KIAA0887, UBXD8, UBXN3B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||ETEA, KIAA0887, UBXD8, UBXN3B|
|Function||May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.|
|Cellular Location||Cytoplasm. Lipid droplet. Endoplasmic reticulum|
|Tissue Location||Broadly expressed, with highest levels in brain.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is highly expressed inperipheral blood of patients with atopic dermatitis (AD), comparedto normal individuals. It may play a role in regulating theresistance to apoptosis that is observed in T cells and eosinophilsof AD patients.
Phan, V.T., et al. Mol. Cell. Biol. 30(9):2264-2279(2010)Ernst, R., et al. Mol. Cell 36(1):28-38(2009)Alexandru, G., et al. Cell 134(5):804-816(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Imai, Y., et al. Biochem. Biophys. Res. Commun. 297(5):1282-1290(2002)
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