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GAS2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43903
Clone Names 110819066
Peptide ID 110819066
Additional Information
Gene ID 2620
Other Names Growth arrest-specific protein 2, GAS-2, GAS2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAS2
Function May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).
Cellular Location Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth- arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity).
Tissue Location Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen
Research Areas
Citations (0)

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The protein encoded by this gene is a caspase-3 substratethat plays a role in regulating microfilament and cell shapechanges during apoptosis. It can also modulate cell susceptibilityto p53-dependent apoptosis by inhibiting calpain activity. Multiplealternatively spliced variants, encoding the same protein, havebeen identified.


Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Benetti, R., et al. J. Biol. Chem. 280(23):22070-22080(2005)Tsutsumi, S., et al. Am. J. Hum. Genet. 74(6):1255-1261(2004)Benetti, R., et al. EMBO J. 20(11):2702-2714(2001)

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$ 80.00
Cat# BP18918a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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