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RRAGB Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q5VZM2
Clone Names 110717167
Peptide ID 110717167
Additional Information
Gene ID 10325
Other Names Ras-related GTP-binding protein B, Rag B, RagB, RRAGB (HGNC:19901)
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RRAGB (HGNC:19901)
Function Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway.
Cellular Location Cytoplasm. Lysosome
Research Areas
Citations (0)

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Ras-homologous GTPases constitute a large family of signaltransducers that alternate between an activated, GTP-binding stateand an inactivated, GDP-binding state. These proteins representcellular switches that are operated by GTP-exchange factors andfactors that stimulate their intrinsic GTPase activity. All GTPasesof the Ras superfamily have in common the presence of six conservedmotifs involved in GTP/GDP binding, three of which arephosphate-/magnesium-binding sites (PM1-PM3) and three of which areguanine nucleotide-binding sites (G1-G3). Transcript variantsencoding distinct isoforms have been identified. [provided byRefSeq].


Ross, M.T., et al. Nature 434(7031):325-337(2005)Tomarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)Sekiguchi, T., et al. J. Biol. Chem. 276(10):7246-7257(2001)Hirose, E., et al. J. Cell. Sci. 111 (PT 1), 11-21 (1998) :Schurmann, A., et al. J. Biol. Chem. 270(48):28982-28988(1995)

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$ 80.00
Cat# BP18936a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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