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RRAGB Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q5VZM2
Clone Names 110717167
Peptide ID 110717167
Additional Information
Gene ID 10325
Other Names Ras-related GTP-binding protein B, Rag B, RagB, RRAGB (HGNC:19901)
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RRAGB (HGNC:19901)
Function Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Cellular Location Cytoplasm. Lysosome
Research Areas
Citations (0)

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Ras-homologous GTPases constitute a large family of signaltransducers that alternate between an activated, GTP-binding stateand an inactivated, GDP-binding state. These proteins representcellular switches that are operated by GTP-exchange factors andfactors that stimulate their intrinsic GTPase activity. All GTPasesof the Ras superfamily have in common the presence of six conservedmotifs involved in GTP/GDP binding, three of which arephosphate-/magnesium-binding sites (PM1-PM3) and three of which areguanine nucleotide-binding sites (G1-G3). Transcript variantsencoding distinct isoforms have been identified. [provided byRefSeq].


Ross, M.T., et al. Nature 434(7031):325-337(2005)Tomarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)Sekiguchi, T., et al. J. Biol. Chem. 276(10):7246-7257(2001)Hirose, E., et al. J. Cell. Sci. 111 (PT 1), 11-21 (1998) :Schurmann, A., et al. J. Biol. Chem. 270(48):28982-28988(1995)

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$ 80.00
Cat# BP18936a
Availability: In Stock
Bulk Size
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