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SLCO1B3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NPD5
Clone Names 100311251
Peptide ID 100311251
Additional Information
Gene ID 28234
Other Names Solute carrier organic anion transporter family member 1B3, Liver-specific organic anion transporter 2, LST-2, Organic anion transporter 8, Organic anion-transporting polypeptide 8, OATP-8, Solute carrier family 21 member 8, SLCO1B3, LST2, OATP1B3, OATP8, SLC21A8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLCO1B3
Synonyms LST2, OATP1B3, OATP8, SLC21A8
Function Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver.
Cellular Location Basolateral cell membrane; Multi-pass membrane protein
Tissue Location Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder
Research Areas
Citations (0)

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SLCO1B3 belongs to the organic anion transporter (OATP)family. OATPs are involved in the membrane transport of bile acids,conjugated steroids, thyroid hormone, eicosanoids, peptides, andnumerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed14993604]).


Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)Weiner, M., et al. Antimicrob. Agents Chemother. 54(10):4192-4200(2010)Kang, T.W., et al. Hum. Mol. Genet. 19(18):3672-3678(2010)Takahashi, N., et al. J. Hum. Genet. (2010) In press :Justenhoven, C., et al. Breast Cancer Res. Treat. (2010) In press :

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$ 80.00
Cat# BP18964b
Availability: In Stock
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