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MLC1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15049
Clone Names 100311267
Peptide ID 100311267
Additional Information
Gene ID 23209
Other Names Membrane protein MLC1, MLC1, KIAA0027, WKL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MLC1
Synonyms KIAA0027, WKL1
Function Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Cellular Location Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum
Tissue Location Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus
Research Areas
Citations (0)

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Background

The function of this gene product is unknown; however,homology to other proteins suggests that it may be an integralmembrane transporter. Mutations in this gene have been associatedwith megalencephalic leukoencephalopathy with subcortical cysts, anautosomal recessive neurological disorder. Alternatively splicedtranscript variants encoding different isoforms have beenidentified.

References

Yis, U., et al. Turk. J. Pediatr. 52(2):179-183(2010)Lanciotti, A., et al. Neurobiol. Dis. 37(3):581-595(2010)Shukla, P., et al. Prenat. Diagn. 28(4):357-359(2008)Ambrosini, E., et al. Mol. Cell. Neurosci. 37(3):480-493(2008)Selch, S., et al. Biol. Psychiatry 61(10):1211-1214(2007)

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$ 80.00
Cat# BP18966b
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