SYTL4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96C24 |
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Clone Names | 100318277 |
Gene ID | 94121 |
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Other Names | Synaptotagmin-like protein 4, Exophilin-2, Granuphilin, SYTL4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SYTL4 |
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Function | Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity). |
Cellular Location | Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Note=Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles (By similarity) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the synaptotagmin likeprotein family. Members of this family are characterized by anN-terminal Rab27 binding domain and C-terminal tandem C2 domains.The encoded protein binds specific small Rab GTPases and isinvolved in intracellular membrane trafficking. This protein bindsRab27 and may be involved in inhibiting dense core vesicleexocytosis. Alternate splicing results in multiple transcriptvariants that encode the same protein.
References
Plaisance, V., et al. J. Biol. Chem. 281(37):26932-26942(2006)Ciufo, L.F., et al. Mol. Biol. Cell 16(2):470-482(2005)Fukuda, M. J. Biol. Chem. 278(17):15390-15396(2003)Fukuda, M., et al. J. Biol. Chem. 277(42):39673-39678(2002)Torii, S., et al. Mol. Cell. Biol. 22(15):5518-5526(2002)
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