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SLCO1C1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NYB5
Clone Names 100324034
Peptide ID 100324034
Additional Information
Gene ID 53919
Other Names Solute carrier organic anion transporter family member 1C1, Organic anion transporter F, OATP-F, Organic anion transporter polypeptide-related protein 5, OAT-RP-5, OATPRP5, Organic anion-transporting polypeptide 14, OATP-14, Solute carrier family 21 member 14, Thyroxine transporter, SLCO1C1, OATP14, OATP1C1, OATPF, SLC21A14
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLCO1C1
Synonyms OATP14, OATP1C1, OATPF, SLC21A14
Function Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein Note=Expressed in both luminal and abluminal membranes of brain capillary endothelial cells. Localized to the apical membrane and basal surfaces of choroid plexus (By similarity).
Tissue Location Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
Research Areas
Citations (0)

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This gene encodes a member of the organic aniontransporter family. The encoded protein is a transmembrane receptorthat mediates the sodium-independent uptake of thyroid hormones inbrain tissues. This protein has particularly high affinity for thethyroid hormones thyroxine, tri-iodothyronine and reversetri-iodothyronine. Polymorphisms in the gene encoding this proteinmay be associated with fatigue and depression in patients sufferingfrom hyperthyroidism. Alternative splicing results in multipletranscript variants.


Franke, R.M., et al. Pharmacogenomics 10(3):339-344(2009)Heuer, H., et al. Endocrinology 150(3):1078-1083(2009)Leuthold, S., et al. Am. J. Physiol., Cell Physiol. 296 (3), C570-C582 (2009) :Westholm, D.E., et al. Endocrinology 150(2):1025-1032(2009)Roberts, L.M., et al. Endocrinology 149(12):6251-6261(2008)

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$ 80.00
Cat# BP18974b
Availability: In Stock
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