|Other Names||Potassium voltage-gated channel subfamily G member 2, Cardiac potassium channel subunit, Voltage-gated potassium channel subunit Kv62, KCNG2, KCNF2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Detected at low levels in brain, lung and placenta|
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Provided below are standard protocols that you may find useful for product applications.
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. This gene encodes a member ofthe potassium channel, voltage-gated, subfamily G. This member is agamma subunit of the voltage-gated potassium channel. Thedelayed-rectifier type channels containing this subunit maycontribute to cardiac action potential repolarization. [provided byRefSeq].
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)Zhu, X.R., et al. Recept. Channels 6(5):337-350(1999)
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