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TRIM58 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8NG06
Clone Names 100408343
Additional Information
Gene ID 25893
Other Names E3 ubiquitin-protein ligase TRIM58, 632-, Protein BIA2, Tripartite motif-containing protein 58, TRIM58
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM58
Function E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
Tissue Location Expressed in erythroblasts.
Research Areas
Citations (0)
citation

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Background

TRIM58 belongs to the TRIM/RBCC family of proteins. it contains a B box-type zinc finger domain, a B30.2/SPRY domain and a RING-type zinc finger domian.

References

Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)

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$ 277.78
Cat# BP18986b
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